Cancer Prevention and Cancer Control Protocols
Cancer clinical trials are research studies for developing better ways of detecting, treating, and eventually preventing cancer. By taking part in a clinical trial, you are among the first to receive new research treatments before they are widely available. Your participation in a clinical trial will influence the future direction of cancer care.
If you are interested in participating in a clinical trial, consult with your physician. Please note: clinical trials are not risk free. Patients must explore the options that are best for their individuals needs with the help of their physician.
Brain/CNS
ANBL0032: Phase III Randomized Study of Chimeric Anti-GD2 in High Risk Neuroblastoma Following Myeloablative Therapy and Autologous Stem Cell Rescue
Physician Summary:
< age 30; High Risk: Anti-GD2 Following ASCR
Breast
NSABP DMP-1: A Study to Evaluate Different Decision-Making Approaches Used by Women Known to be at Increased Risk for Breast Cancer
Physician Summary:
Women > Age 35; Increased risk of breast cancer as determined by physician. Intervention: Evaluate Decision Making Process for this group of women
CALGB 70806 - Vitamin D and Breast Cancer Biomarkers (limited to Saint Mary's Health Care only)
Physician Summary:
< Age 55; FSH < 20; Staging: Vitamin D Levels; Treatment: Vitamin D /Placebo
The FAMILY (Facing A Maternal Illness in Latency Years) Project
Physician Summary:
Questionnaires for mothers who have been diagnosed with breast cancer within the past 6 months and their child/children ages 6-12
70305: A Randomized Study to Prevent Lymphedema in Women Treated For Breast Cancer
Physician Summary:
Newly Diagnosed Stage I – IV: Study to Prevent Lymphedema. Tx: Step 1: Phsical Assessments and Questionnaires; Step 2: Education vs Education & PT Intervention.
NSABP/NCIC CTC MA.32.F: Biobehavioral Mechanisms of Fatigue in Patients Treated on NCIC CTG MA.32: A Phase III Randomized Trial of Metformin Versus Placebo on Recurrence and Survival in Early Stage Breast Cancer
Physician Summary:
Companion study to CTSU MA.32. Bio-Specimen Collection and Patient Questionnaires.
CTSU SCUSF 0806: Phase II placebo-controlled trial of lisinopril and Coreg CR® to reduce cardiotoxicity in patients with breast cancer receiving (neo) adjuvant chemotherapy with trastuzumab (Herceptin ®)
Physician Summary:
> Age 18 and HER2 Positive; Adjuvant or Neo-Adjuvant Patients scheduled to receive Herceptin with or after primary chemotherapy. TX: Lisinopril or Coreg or Placebo
NSABP B-43: A Phase III Clinical Trial Comparing Trastuzumab Given Concurrently with Radiation Therapy and Radiation Therapy Alone for Women with HER2-Positive Ductal Carcinoma In Situ Resected by Lumpectomy
Physician Summary:
≥ age 18, Central HER2 Testing: RT +/- Trastuzumab
Cancer Control
NSABP DMP-1: A Study to Evaluate Different Decision-Making Approaches Used by Women Known to be at Increased Risk for Breast Cancer
Physician Summary:
Women > Age 35; Increased risk of breast cancer as determined by physician. Intervention: Evaluate Decision Making Process for this group of women
CALGB 70806 - Vitamin D and Breast Cancer Biomarkers (limited to Saint Mary's Health Care only)
Physician Summary:
< Age 55; FSH < 20; Staging: Vitamin D Levels; Treatment: Vitamin D /Placebo
The FAMILY (Facing A Maternal Illness in Latency Years) Project
Physician Summary:
Questionnaires for mothers who have been diagnosed with breast cancer within the past 6 months and their child/children ages 6-12
NSABP/NCIC CTC MA.32.F: Biobehavioral Mechanisms of Fatigue in Patients Treated on NCIC CTG MA.32: A Phase III Randomized Trial of Metformin Versus Placebo on Recurrence and Survival in Early Stage Breast Cancer
Physician Summary:
Companion study to CTSU MA.32. Bio-Specimen Collection and Patient Questionnaires.
70305: A Randomized Study to Prevent Lymphedema in Women Treated For Breast Cancer
Physician Summary:
Newly Diagnosed Stage I – IV: Study to Prevent Lymphedema. Tx: Step 1: Phsical Assessments and Questionnaires; Step 2: Education vs Education & PT Intervention.
URCC 10055: Assessment of Cognitive Function in Breast Cancer and Lymphoma Patients Receiving Chemotherapy at Pre-Treatment, Post-Treatment, and at Six Month Follow-Up
Physician Summary:
Invasive Breast Cancer Stage I-IIIC or High-Grade Lymphoma; Chemo Naïve. Patient to complete three Questionnaires.
CTSU SCUSF 0806: Phase II placebo-controlled trial of lisinopril and Coreg CR® to reduce cardiotoxicity in patients with breast cancer receiving (neo) adjuvant chemotherapy with trastuzumab (Herceptin ®)
Physician Summary:
> Age 18 and HER2 Positive; Adjuvant or Neo-Adjuvant Patients scheduled to receive Herceptin with or after primary chemotherapy. TX: Lisinopril or Coreg or Placebo
NSABP B-43: A Phase III Clinical Trial Comparing Trastuzumab Given Concurrently with Radiation Therapy and Radiation Therapy Alone for Women with HER2-Positive Ductal Carcinoma In Situ Resected by Lumpectomy
Physician Summary:
≥ age 18, Central HER2 Testing: RT +/- Trastuzumab
NSABP P-5: Statin Polyp Prevention Trial in Patients with Resected Colon Cancer
Physician Summary:
> Age 18. Staging: Stage I or II, adenocarcinoma of the colon. Treatment: Rosuvastatin (Crestor) vs Placebo
MD Anderson 2007-0914A - (PREDICT) A Multi-Center Study in Patients Undergoing Anthracycline-Based Chemotherapy to Assess the Effectiveness of Using Biomarkers to Detect and Identify Cardiotoxicity and Describe Treatment
Physician Summary:
Age 18-85 Years; New Course of Chemo w/Anthracycline. Treatment: BNP and Troponin I Prior to each Tx Cycle.
N08C1: Paclitaxel-Associated Acute Pain Syndrome Natural History Study Please Note: Only Arms A & D are open.
Physician Summary:
≥ age 18; Any Staging: Standard of Care with Use of Paclitaxel
RC08C6: White Wine for Appetite Loss: A Randomized, Controlled Non-blinded Trial
Physician Summary:
Temp Closed! 2004-0024: Chemotherapy and Mindfulness Relaxation: A Randomized Trial At M.D. Anderson Cancer Center and M.D. Anderson Community Clinical Oncology Program
Physician Summary:
Chemotherapy & Mindfulness Relaxation/Randomized Trial
SWOG S0702: A Prospective Observational Multicenter Cohort Study to Assess the Incidence of Osteonecrosis of the Jaw (ONJ) in Cancer Patients With Bone Metastasis Starting Zoledronic Acid Treatment
Physician Summary:
≥ age 18; Bone Mets: Assess ONJ in Patients receiving Zometa
NCCTG N09C6: Randomized Double-Blind Study of Doxepin Rinse versus Placebo in the Treatment of Acute Oral Mucositis Pain in Patients Receiving Radiotherapy with or without Chemotherapy. (Not available at Mercy Health Partners or Battle Creek Health System)
Physician Summary:
> Age 18; Painful Mucositis; Must be receiving Radiotherapy w/ 1/3 of oral cavity included in the radiation therapy fields. Treatment: Doxepin/Placebo
Gastrointestinal
NSABP P-5: Statin Polyp Prevention Trial in Patients with Resected Colon Cancer
Physician Summary:
> Age 18. Staging: Stage I or II, adenocarcinoma of the colon. Treatment: Rosuvastatin (Crestor) vs Placebo
Leukemia
8461: Cytogenetic Studies In Acute Leukemia
Physician Summary:
Previously Untreated AML, ALL, MDS: Bone Marrow and Blood Samples (Ancillary CALGB 9665 Required)